Student Publications

Tsaoussoglou M, Lianou L, Maragozidis P, Hatzinikolaou S, Mavromati M, Orologas N, Panaghiotopoulou-Gartagani P, Rassidakis G, Balatsos NA, Chrousos G, Kaditis AG. 2012. Cysteinyl leukotriene receptors in tonsillar Band T-lymphocytes from children withobstructive sleep apnea. Sleep Med. 13(7):879-885. PMID: 22647498 DOI: 10.1016/j.sleep.2012.03.010

Parmenopoulou V, Chatzileontiadou DS, Manta S, Bougiatioti S, Maragozidis P, Gkaragkouni DN, Kaffesaki E, Kantsadi AL, Skamnaki VT, Zographos SE, Zounpoulakis P, Balatsos NA, Komiotis D, Leonidas DD. 2012. Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg Med Chem. 20(24):7184-7193. PMID: 23122937 DOI: 10.1016/j.bmc.2012.09.067

Kantsadi AL, Manta S, Psarra AM, Dimopoulou A, Kiritsis C, Parmenopoulou V, Skamnaki VT, Zoumpoulakis P, Zographos SE, Leonidas DD, Komiotis D. 2012. The binding of C5-alkynyl and alkylfurano[2,3- d] pyrimidineglucopyranonucleosides to glycogen phosphorylase b: synthesis, biochemical and biological assessment. Eur J Med Chem. 54:740-749. PMID: 22770609 DOI: 10.1016/j.ejmech.2012.06.029

Manta S, Kiritsis C, Dimopoulou A, Parmenopoulou V, Kollatos N, TsotinisA, Komiotis D. 2013. Unsaturation: An Important Structural Feature to Nucleosides’ Antiviral Activity. Anti-Infective Agents, 12(1): 2-57. DOI: 10.2174/22113525113119990106

Kiritsis C, Manta S, Parmenopoulou V, Dimopoulou A, Kollatos N, Papasotiriou I, Balzarini J, Komiotis D. 2012. Stereocontrolled synthesis of 4'- C-cyano and 4'-C-cyano-4' deoxy pyrimidine pyranonucleosides as potentialchemotherapeutic agents. Carbohydr Res. 364:8-14. PMID: 23147040 DOI: 10.1016/j.carres.2012.10.012

Manta S, Parmenopoulou V, Kiritsis C, Dimopoulou A, Kollatos N, Papasotiriou I, Balzarini J, Komiotis D. 2012. Stereocontrolled facile synthesis and biological evaluation of (3'S) and (3'R)-3'-amino (and Azido)-3'- deoxypyranonucleosides. Nucleosides Nucleotides Nucleic Acids. 31(7):522- 535. PMID: 22849646 DOI: 10.1080/15257770.2012.696759

Manta S, Xipnitou A, Kiritsis C, Kantsadi AL, Hayes JM, Skamnaki VT, Lamprakis C, Kontou M, Zoumpoulakis P, Zographos SE, Leonidas DD, Komiotis D. 2012. 3'-axial CH2 OH substitution on glucopyranose does not increase glycogen phosphorylase inhibitory potency. QM/MM-PBSA calculations suggest why. ChemBiol Drug Des. 79(5):663-673. PMID: 22296957 DOI: 10.1111/j.1747-0285.2012.01349.x

Kantsadi AL, Hayes JM, Manta S, Skamnaki VT, Kiritsis C, Psarra AM, Koutsogiannis Z, Dimopoulou A, Theofanous S, Nikoleousakos N, Zoumpoulakis P,Kontou M, Papadopoulos G, Zographos SE, Komiotis D, Leonidas DD. 2012. The σ-hole phenomenon of halogen atoms forms the structural basis of the strong inhibitory potency of C5halogen substituted glucopyranosyl nucleosides towards glycogen phosphorylase b. ChemMedChem. 7(4):722-732. https://doi.org/10.1002/cmdc.201100533

Kiritsis C, Manta S, Parmenopoulou V, Balzarini J, Komiotis D. 2011. Branched-chain C-cyanopyranonucleosides: synthesis of 3'-C-cyano & 3'-Ccyano-3'-deoxy pyrimidinepyranonucleosides as novel cytotoxic agents. Eur J Med Chem. 46(11):5668-5674. PMID: 21917363 PMCID: PMC7115479 DOI: 10.1016/j.ejmech.2011.08.033

Spanou C, Tzioumaki N, Manta S, Margaris P, Kouretas D, KomiotisD, Liadaki K. 2011. Unsaturated Keto and ExomethylenePyranonucleoside Analogues of Thymine and Uracil Exhibit Potent Antioxidant Properties. Pharmacology and Pharmacy, 2 (3): 122-126 DOI: 10.4236/pp.2011.23016